Researcher

Memphis, TN

About St. Jude Children's Research Hospital

The World’s Most Dedicated Never Give Up

There’s a reason St. Jude Children’s Research Hospital is recognized as a great place to work. Because at our world-class pediatric research hospital, every one of our professionals shares our commitment to make a difference in the lives of the children we serve. There’s a unique bond when you’re part of a team that gives their all to advance the treatments and cures of pediatric catastrophic diseases. The result is a collaborative, positive environment where everyone, regardless of their role, receives the resources, support and encouragement to advance and grow their careers and be the force behind the cures.

Researcher

At St. Jude Children’s Research Hospital, we offer state-of-the-art technologies, extraordinary support and a collaborative, bench-to-bedside environment. The Guenther Lab is seeking an outstanding, highly motivated, team-oriented candidate for a Researcher or Senior Researcher level position to join our efforts in advancing therapeutic targets for osteosarcoma, a rare but aggressive pediatric bone tumor.

 

The Guenther lab utilizes genome-scale CRISPR screening and other complementary chemical and genomic screening modalities in pre-clinical models to uncover novel dependencies, or critical osteosarcoma-specific survival genes. We are interested in the validation of these osteosarcoma-specific vulnerabilities for new biologic insights and therapeutic interventions. Recently, research in the Guenther laboratory has identified several genes involved in DNA damage repair that may be biologically relevant in this disease. The lab is specifically interested in the biologic investigation of these pathways in osteosarcoma and how they may be optimally exploited for patient care.

 

 

The successful candidate will: 1) support efficient laboratory operations and 2) provide technical support for ongoing laboratory projects, including collecting and analyzing data.

 

Excellent written and communication skills as well as direct experience with mouse handling, basic molecular biology/biochemical laboratory techniques, mammalian cell culture and molecular cloning are required for this position. Candidates should be able to communicate effectively and work both independently and as part of a team of scientists, bioinformaticians, and trainees, and execute tasks in an organized and timely manner.

 

The World’s Brightest Minds Always Innovate 

 

At St. Jude Children’s Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That’s why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big, and we give you everything you need to be the force behind our cures. 

  • Support efficient laboratory operations
  • Provide technical support for ongoing laboratory projects, including collecting and analyzing data.
  • Utilize excellent written and communication skills to disseminate findings
  • Perform basic molecular biology/biochemical laboratory techniques including mammalian cell culture and molecular cloning 
  • Work both independently and as part of a team of scientists, bioinformaticians, and trainees
  • Execute tasks in an organized and timely manner
  • Murine breeding and handling
  • Various tasks as assigned
  • no additional experience required